118th ITC:
Cell heterogeneity & tissue architechture

We have entered an era where we can profile the transcriptome and gene regulatory network of individual cells, and use this information to redefine what we mean by a cell type. This has the potential to provide powerful new insights into developmental biology, physiology and disease etiology. However, most single cell analyses have been applied to cells in suspension - e.g. from the haematopoietic and immune systems and cells have generally been considered as individual self–contained units. By contrast, most cells in the body exist in solid tissues with defined cell–cell contacts, polarities and position within a complex 3D tissue architecture.

This meeting aims to bring together researchers from very diverse communities: those experi-mentally investigating tissue architecture and gene regulation, those generating ex vivo organoid models of tissues, and computational scientists and mathematicians interested in analysing and modelling these complex datasets. By bringing together these groups of scientists, we will discuss progress towards understanding how different cell types are formed, communicate with each other and work together to form and maintain tissues.



Wendy A. Bickmore (Edinburgh, United Kingdom)
Sarah A. Teichmann (Hinxton, Cambridge, United Kingdom)



10-14 October 2018
(Participation by invitation only)



Adey, Andrew (Portland, OR, USA)
Barker, Nicholas (Singapore, Singapore)
Bhatia, Shipra (Edinburgh, United Kingdom)
Blanpain, Cédric (Bruxelles, Belgium)
Bodenmiller, Bernd (Zurich, Switzerland)
Bonev, Boyan (Montpellier, France)
Bressan, Dario (Cambridge, United Kingdom)
Dzierzak, Elaine (Edinburgh, United Kingdom)
Ezhkova, Elena (New York, NY, USA)
Grün, Dominic (Freiburg, Germany)
Haniffa, Muzlifah (Newcastle upon Tyne, United Kingdom)
Hemberg, Martin (Hinxton, Cambridge, United Kingdom)
Itzkovitz, Shalev (Rehovot, Israel)
Jones, Phil H. (Hinxton, Cambridge, United Kingdom)
Kind, Jop (Utrecht, The Netherlands)
Kirschner, Marc (Boston, MA, USA)
Lindsay, Susan (Newcastle upon Tyne, United Kingdom)
Lundberg, Emma (Stockholm, Sweden)
Lundeberg, Joakim (Solna, Sweden)
Marioni, John (Hinxton, Cambridge, United Kingdom)
Martinez-Jimenez, Celia P. (Cambridge, United Kingdom)
Ponting, Chris P. (Edinburgh, United Kingdom)
Reddington, James (Heidelberg, Germany)
Sauka-Spengler, Tatjana (Oxford, United Kingdom)
Scialdone, Antonio (Neuherberg, Germany)
Singer, Meromit (Cambridge, MA, USA)
Steel, Karen (London, United Kingdom)
Sudmant, Peter H. (Cambridge, MA, USA)
Theis, Fabian J. (Neuherberg, Germany)
Trapnell, Cole (Seattle, WA, USA)
Vallejos, Catalina (Edinburgh, United Kingdom)
van Oudenaarden, Alexander (Utrecht, The Netherlands)
Villani, Alexandra-Chloé (Cambridge, MA, USA)
Voet, Thierry (Hinxton, Cambridge, United Kingdom)


Coming in March 2019:

119th ITC:
Tissue formation and regeneration: from molecules to models


Elly Tanaka (Vienna, Austria)
Peter Reddien (Cambridge, MA, USA)
James Sharpe (Barcelona, Spain)


27-31 March 2019

passion for science